西罗莫司脂化物
Temsirolimus 是 mTOR 抑制剂，IC50 值为 1.76 μM。
产品名称
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中文名西罗莫司脂化物
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英文名Temsirolimus
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中文别名替西罗莫司 | 西罗莫司 | 坦西莫司
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英文别名
CCL-779 TeMsiroliMus (~) Torisel Temsirolimus [14C]-Temsirolimus 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin Propanoic acid, 3-hydroxy-2-(hydroxymethyl)-2-methyl-, (1R,2R,4S)-2-methoxy-4-[(2R)-2-[(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,26R,27R,34aS)-1,4,5,6,9,10,11,12,13,14,21,22,23,24,25,26,27,28,29,31,32,33,34,34a-tetracosahydro-9,27-dihydroxy-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-1,5,11,28,29-pentaoxo-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontin-3-yl]propyl]cyclohexyl ester Rapamycin (42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate] TeMsiroliMus (Torisel) Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate rapaMycin 42-ester with 3-hydroxy-2-(hydroxyMethyl)-2-Methylpropionic acid (1R,2R,4S)-4-{(2R)-2-[(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-1,5,11,28,29-pentaoxo-1,4,5,6,9,10,11,12,13,14,21,22,23,24,25,26,27,28,29,31,32,33,34,34a-tetracosahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontin-3-yl]propyl}-2-methoxycyclohexyl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate (1R,2R,4S)-4-{(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,35R)-1,18-Dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.0] hexatriaconta-16,24,26,28-tetraen-12-yl]propyl}-2-methoxycyclohexyl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate NSC 683864 -
常用名西罗莫司脂化物
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C A S号162635-04-3
物理性质
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密度1.2±0.1 g/cm3
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沸点1048.4±75.0 °C at 760 mmHg
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熔点99-101ºC
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化学式C56H87NO16
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结构式
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闪点587.8±37.1 °C
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分子量1030.287
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精确质量1029.602539
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P S A241.96000
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外观形状white to off-white
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储存条件-20°C Freezer
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稳定性
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水溶解性
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形态
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H L B值
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粘度
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PH值
作用/用途
Temsirolimus 是 mTOR 抑制剂，IC50 值为 1.76 μM。
制备方法
安全提醒
MSDS
原料简介
应用范围
毒性和生态
安全信息
| 安全声明 (欧洲) | 24/25 |
|---|---|
| 危险品运输编码 | NONH for all modes of transport |
| RTECS号 | VE6257000 |
| 海关编码 | 29349990 |
是否危险品
危险性
危险类别码
危险等级
触发危险方式
安全技术说明书
环境影响程度
包装与储运
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